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11-Mar-2019 20:44

The hypothesis embraced by the authors of the study is that the likely source for the harmine in these two samples was the ayahuasca vine, which must have been imported, over some distance and rough terrain, from the Upper Amazon. The absence of 5-Me O-DMT in the hair samples would then indicate that the ayahuasca vine was consumed without the addition of a DMT-containing companion plant. A quick search of ayahuasca tourist and related websites reveals virtually identical statements of this claim: “The use of Ayahuasca has been recorded over 5000 years ago by the natives of Amazon and surrounding areas,” “Ayahuasca has been known to people for over 5000 years,” “This plant medicine has been used for over 5000 years throughout the Amazonian basin,” “Ayahuasca has been used for over 5000 years.” These examples could be multiplied. Just for perspective, the date of 3000 BC would make the origins of the ayahuasca drink as old as the founding of the first Egyptian dynasty, five centuries older than the reign of the Sumerian king Gilgamesh, and almost ten centuries older than the earliest South American devices yet discovered for the ingestion of DMT-containing plants—two pipes found in association with seeds in northwest Argentina, which have been radiocarbon dated to 2130 BC, and which had residues that tested positive for DMT (Torres, 1995, p. And while it is true that the parenteral ingestion of DMT-containing plants is of considerable antiquity in South America, there is no corresponding archeological or documentary evidence prior to the eighteenth century for the combination of a DMT-containing plant with the ayahuasca vine for oral ingestion.But first: Why such extraordinary claims for which support is so thin? The first is that, in an attempt to legitimate ayahuasca use, its proponents invoke the culturally resonant trope of a millennia-old indigenous wisdom.But DMT, when taken orally, is inactivated by peripheral monoamine oxidase-A, an enzyme found in the lining of the stomach, whose function is precisely to oxidize molecules containing an NH ingestion—using a route other than the digestive tract, such as smoking, injection, or inhalation—which bypasses the MAO in the stomach lining.For example, a number of indigenous peoples around the Orinoco Basin in Venezuela inhale a snuff called that prevents the breakdown of DMT in the digestive tract.Here too we find clear evidence of the use of an Tiwanaku culture produced a variety of small carved objects that included puma and jaguar effigies, incense burners, and highly decorated snuffing tablets and tubes.

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One possibility is that the Tiwanakuans consumed the ayahuasca vine by itself medicinally for its emetic and purgative properties, or, without a companion plant, for its independent visionary effects. B., Chan, K., Mc Kenna, D., Llagostera, A., & Schultes, R.

However, as Trout (2008) points out, the absence of 5-Me O-DMT from the hair samples is difficult to evaluate, given our current ignorance of whether this tryptamine is detectable in hair at all.



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